Elevated Level of CD4+ T Cell Immune Activation in Acutely HIV-1-Infected Stage Associates With Increased IL-2 Production and Cycling Expression, and Subsequent CD4+ T Cell Preservation
Persistent immune activation is a striking consequence of HIV-1 infection and a driving force of CD4+ T cell depletion and AIDS events during chronic infection.High level of T cell immune activation associates with antiretroviral therapy (ART)-treated clinical outcomes in chronically HIV-1-infected patients.However, the role of T cell activation du